The micro-polymer technology provides superior sensitivity and minimum cross-reactivity to endogenous mouse and rat IgG. The product line includes specially formulated heat-retrieval solutions, blocking agents, and one- and two-step detection reagents.
- High staining sensitivity and specificity
- Minimum cross-reactivity to endogenous IgG with proprietary blocking reagents
- Elimination of endogenous biotin
- Reduced number of IHC steps
- Use with formalin-fixed, paraffin-embedded tissues, floating sections, frozen sections and cell culture preparations
- Highly effective ancillary reagents
- Suitable for both manual and automated techniques
Animal tissues contain endogenous immunoglobulins that produce significantly high levels of background staining when standard anti-mouse/anti-rabbit detection systems are employed. Menarini provides micro-polymer detection systems for use with primary antibodies from various sources (mouse, rat, rabbit, goat) on a range of tissues (mouse, rat, canine, feline, bovine, equine, porcine, ovine) which result in reduced background staining and higher sensitivity.
Mouse primary antibodies
This novel detection technology allows for use of mouse primary antibodies on mouse and rat tissues.
|Mouse-on-mouse HRP-polymer bundle||MP-510-MMK|
|Rat detection kit for anti-mouse CD31||MP-517-RTK6|
Rat primary antibodies
Use with rat monoclonal antibodies on mouse tissues. The Rat-on-Mouse HRP / AP micro-polymer detection is a two-step system. It is comprised of two reagents: a rat probe that binds to the rat primary antibody; and an HRP / AP micro-polymer that conjugates to the probe.
|Rat detection kit for Anti-mouse CD31||MP-517-RTK6|
Rabbit primary antibodies
Rabbit-on-Rodent detection is available as a micro-polymer only.
Goat-on-rodent primary antibodies
Use with goat primary antibodies on mouse, rat and human tissues. The goat detection is a two-step system.
Retrieval and blocking agents
Blocking and HIER reagents to enhance specificity and reduce/eliminate background.
|Rat background blocker||MP-962|
|Mouse background blocker||MP-961|
|Rat super background blocker||MP-964|
|Mouse super background blocker||MP-963|
|Access rodent, x10||MP-913|
Canine micro-polymer detection
The Mouse-on-Canine and Rabbit-on-Canine detection polymers are specially designed for use on canine and feline tissues. With advanced polymer technology and a proprietary potent blocker, the detection polymers provide increased sensitivity, reduced IHC steps (no Avidin/Biotin block or Link/Probe), and virtually eliminate cross-reactivity to endogenous canine and feline IgG. These kits can be used with paraffin-embedded tissues, floating sections and frozen sections. Canine detection is suitable for both manual and automated systems such as the intelliPATH™.
Mouse and rabbit-on-rodent double stain
This multiplex polymer detection is specifically designed for use on rat and mouse tissue. The 5-step procedure for detecting multiple antigens on a single slide can be done in approximately two hours using a simultaneous protocol. Staining time is reduced from 4-6 hours to approximately 2 hours by eliminating several steps: avidin-biotin blocking steps, elution step and sequential staining steps. The advanced micro-polymer technology provides simplified procedures, increased sensitivity and virtually eliminates background staining. Potent blockers such as mouse background blocker or rat background blocker eliminate endogenous mouse or rat IgG background for the most difficult of tissues including: lymph, spleen, lung, kidney and liver.
|Rat and mouse double stain kit||MP-RDS513|
Canine and feline tissues